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Four Syosset Students Named 2022 Regeneron Science Talent Scholars

Four Syosset High School Students have been named 2022 Regeneron Science Talent Search (Regeneron STS) Scholars. Congratulations to Syosset High School seniors Sabrina Chen, Ethan Chiu, Rohan Ghotra and Eric Huang. The Regeneron STS is the nation’s oldest and most prestigious pre-college science competition.

These students were selected from 1,804 U.S. and international high school students who submitted original research in critically important scientific fields of study. They are among 300 students named Regeneron STS scholars and hope to be among 40 finalists named later this month. Each scholar will receive a $2,000 award with an additional $2,000 per scholar going to the high school to support STEM education. STS scholars are selected based on their exceptional research skills, commitment to academics, innovative thinking and promise as scientists as demonstrated through the submission of their original, independent research projects, essays, and recommendation.

“Being named a Regeneron Science Talent Search Scholar is a remarkable accomplishment,” remarked Syosset High School research facilitator Veronica Ade. “These students have worked tirelessly throughout their high school careers.  I am impressed by their perseverance and am so proud of their accomplishments.”

Sabrina completed her project “Negative Charges at T168, S169, and/or S170 of ECM11 Promote Wild-Type Meiotic Progression and Synapsis in Saccharomyces cerevisiae Cells” under the direction of Dr. Nancy Hollingsworth at Hollingsworth Laboratory, Stony Brook University.  The importance of Ecm11 and its negative charges in accurate meiotic progression and synapsis were evaluated by mutating the amino acids on the three phosphosites in yeast, or Saccharomyces cerevisiae

Ethan completed his project “Developing a Self-Formed Ectodermal Autonomous Multi-Zone Organoid Model Using Human Stem Cells to Examine the Effect of Doxycycline Treatment in Uveal Melanoma” at the Ichan School of Medicine at Mount Sinai under the direction of Dr. Timothy Blenkinsop.  Ethan studied Uveal Melanoma (UM), the most common deadly eye cancer, and examined the effect of an antibiotic on the genes involved in tumor proliferation. 

Rohan worked under the direction of Dr. Peter Koo at the Koo Laboratory, Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory on his project “Uncovering Motif Interactions from Convolutional Attention Networks for Regulatory Genomics.” He studied computational modeling, in particular artificial intelligence, which is frequently employed for DNA analysis.  Rohan developed a novel pipeline (GLIFAC) for extracting interactions between protein binding sites in the DNA. The proposed technique uses global correlations to statistically validate all local interactions, thus improving accuracy. 

Eric’s project “Compliant and Aerodynamic Characteristics of a 3D Printed Variable Chamber Aircraft Wing,” was completed at Syosset High school under the direction of Ms. Erin O’Rourke. Eric used 3D printing plastic to create a small-scale airplane wing capable of bending when a force was applied. Such a design is beneficial because the wing can alter its aerodynamic characteristics to maximize its efficiency depending on the scenario.  For example, the wing can be set to full-camber during takeoff to maximize lift and can be set to minimum-camber during cruising to minimize drag. 

The 40 finalists in the competition, to be named on January 20, will undergo a rigorous judging process, interact with leading scientists, display their research for the public, meet with national leaders, and compete for more than $1.8 million in awards provided by Regeneron.